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What’s Ulcer No single cause has been found for ulcers. However, it is now clear that an ulcer is the end result of an imbalance between digestive fluids in the stomach and duodenum Who Is More Likely to Get Ulcers? Women and older people are more likely to develop these ulcers. However, a recent study shows that young men are more likely to experience duodenal ulcers, while older women have more gastric ulcers. This has been linked to aspirin use.High intake of aspirin also increases risk. Some experts believe that alcohol, tobacco, and caffeine use contribute to the prevalence of the ulcers. There is very little research to back this up. Still, most doctors agree that people already experiencing the ulcers should stay away from these substances. Cancer patients can be at risk for these ulcers when undergoing radiation treatment or chemotherapy. The ulcers can sometimes go hand in hand with other infections. Conditions such as cystic fibrosis, hepatic cirrhosis, C